BDBM251894 US9475809, 6::US9918969, 6

SMILES FC(F)(F)c1n[nH]c(n1)-c1ccc(NC(=O)Cn2c3CCC(=O)c3c(cc2=O)-c2cc(Cl)ccc2Cl)cc1

InChI Key InChIKey=NXPKWVZEEAKMAK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 251894   

TargetCoagulation factor XI(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM251894(US9475809, 6 | US9918969, 6)
Affinity DataIC50:  550nMAssay Description:The factor XIa inhibition of the inventive substances is determined using a biochemical test system which utilizes the reaction of a peptidic factor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM251894(US9475809, 6 | US9918969, 6)
Affinity DataIC50:  550nMpH: 7.4 T: 2°CAssay Description:The factor XIa inhibition of the inventive substances is determined using a biochemical test system which utilizes the reaction of a peptidic factor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent