BDBM25207 2,4-Pyrimidine derivative, 9::4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-2-N-(2-fluorophenyl)pyrimidine-2,4-diamine

SMILES Fc1ccccc1Nc1nccc(Nc2c3OCOc3ccc2Cl)n1

InChI Key InChIKey=PGWONMQJDLBWPO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25207   

TargetEphrin type-B receptor 4(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM25207(2,4-Pyrimidine derivative, 9 | 4-N-(5-chloro-2H-1,...)
Affinity DataIC50:  5.00E+3nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed