BDBM2521 3-[(2-tert-butyl-5-methylphenyl)sulfanyl]-4-hydroxy-6-[4-(2-hydroxyethoxy)phenyl]-6-(2-phenylethyl)-5,6-dihydro-2H-pyran-2-one::6-Phenyl-6-phenethyldihydropyrone 13j

SMILES Cc1ccc(c(SC2C(=O)CC(CCc3ccccc3)(OC2=O)c2ccc(OCCO)cc2)c1)C(C)(C)C

InChI Key InChIKey=ZHVSQNDTPFBNDP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2521   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM2521(3-[(2-tert-butyl-5-methylphenyl)sulfanyl]-4-hydrox...)
Affinity DataIC50:  12nMpH: 6.2 T: 2°CAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair
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