BDBM25222 2,4-Pyrimidine derivative, 24::2-({4-[(5-chloro-2H-1,3-benzodioxol-4-yl)amino]pyrimidin-2-yl}amino)benzene-1-sulfonamide

SMILES NS(=O)(=O)c1ccccc1Nc1nccc(Nc2c3OCOc3ccc2Cl)n1

InChI Key InChIKey=ZPZZWCZJGVDHOW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25222   

TargetEphrin type-B receptor 4(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM25222(2,4-Pyrimidine derivative, 24 | 2-({4-[(5-chloro-2...)
Affinity DataIC50:  3.55E+4nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed