BDBM25227 2,4-Pyrimidine derivative, 29::4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-2-N-(4-methanesulfonylphenyl)pyrimidine-2,4-diamine

SMILES CS(=O)(=O)c1ccc(Nc2nccc(Nc3c4OCOc4ccc3Cl)n2)cc1

InChI Key InChIKey=BTUJCHUIIMIJSY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25227   

TargetEphrin type-B receptor 4(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM25227(2,4-Pyrimidine derivative, 29 | 4-N-(5-chloro-2H-1...)
Affinity DataIC50:  630nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed