BDBM25230 2,4-Pyrimidine derivative, 32::4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-2-N-[4-(morpholin-4-yl)phenyl]pyrimidine-2,4-diamine

SMILES Clc1ccc2OCOc2c1Nc1ccnc(Nc2ccc(cc2)N2CCOCC2)n1

InChI Key InChIKey=MYFOTLHQMXVWQX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25230   

TargetEphrin type-B receptor 4(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM25230(2,4-Pyrimidine derivative, 32 | 4-N-(5-chloro-2H-1...)
Affinity DataIC50:  1.00E+3nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed