BDBM2525 6-Phenyl-6-phenethyldihydropyrone 13n::6-[2-(3-aminophenyl)ethyl]-3-{[2-tert-butyl-4-(hydroxymethyl)-5-methylphenyl]sulfanyl}-4-hydroxy-6-phenyl-5,6-dihydro-2H-pyran-2-one

SMILES Cc1cc(SC2C(=O)CC(CCc3cccc(N)c3)(OC2=O)c2ccccc2)c(cc1CO)C(C)(C)C

InChI Key InChIKey=OXNYGTOVKODUBX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2525   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM2525(6-Phenyl-6-phenethyldihydropyrone 13n | 6-[2-(3-am...)
Affinity DataIC50:  4nMpH: 6.2 T: 2°CAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed