BDBM25355 8-benzyl-4-(cyclohexylamino)-1-(3-methylbutyl)-1,3,8-triazaspiro[4.5]dec-3-en-2-one::Spiropiperidine Iminohydantoin, 10

SMILES CC(C)CCN1C(=O)N=C(NC2CCCCC2)C11CCN(Cc2ccccc2)CC1

InChI Key InChIKey=UENREBBPIRJWDJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25355   

TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM25355(8-benzyl-4-(cyclohexylamino)-1-(3-methylbutyl)-1,3...)
Affinity DataIC50: >1.00E+5nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. After the reaction was terminated, the solution wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed