BDBM254134 US10112937, Example 12::US10150765, Example 12::US10703749, Example 12::US9464084, 12

SMILES CC1N(CCc2c1ncn2-c1ccccc1)C(=O)c1cccc(c1Cl)C(F)(F)F

InChI Key InChIKey=SAYIMIUULPUCOP-UHFFFAOYSA-N

Data  10 KI  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 254134   

TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM254134(US10112937, Example 12 | US10150765, Example 12 | ...)
Affinity DataIC50:  5nMAssay Description:Antagonist activity at recombinant human P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of Bz-ATP-induced Ca2+ flux preincubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM254134(US10112937, Example 12 | US10150765, Example 12 | ...)
Affinity DataIC50:  766nMAssay Description:Antagonist activity at recombinant rat P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of Bz-ATP-induced Ca2+ flux preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed