BDBM256431 US9487501, 32
SMILES Cc1nn(cc1C(=O)Nc1ccc(cc1)[C@H]1CNCCO1)-c1ccc(OC(F)F)cc1
InChI Key InChIKey=NTWPPCGAVARGHR-HXUWFJFHSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 256431
Affinity DataKi: 0.200nM ΔG°: -13.8kcal/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea...More data for this Ligand-Target Pair
Affinity DataKi: 0.800nM ΔG°: -12.9kcal/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...More data for this Ligand-Target Pair