BDBM25651 4-{1-methyl-4-[4-(1H-pyrazol-3-yl)phenyl]-1H-pyrazol-3-yl}pyridine::pyrazole based inhibitor, 33

SMILES Cn1cc(c(n1)-c1ccncc1)-c1ccc(cc1)-c1cc[nH]n1

InChI Key InChIKey=ZZGACVWRPAHSSW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 25651   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM25651(4-{1-methyl-4-[4-(1H-pyrazol-3-yl)phenyl]-1H-pyraz...)
Affinity DataIC50:  68nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM25651(4-{1-methyl-4-[4-(1H-pyrazol-3-yl)phenyl]-1H-pyraz...)
Affinity DataIC50:  68.4nMAssay Description:Activity of human recombinant B-Raf protein was assessed in vitro by assay of the incorporation of radiolabeled phosphate to recombinant MAP kinase (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed