BDBM256853 US10654855, Example 36::US11236095, Example 36::US9492453, 36
SMILES Cc1c[nH]c2ncnc(N3CCC(N)(CC3)C(=O)N[C@@H](CCO)c3ccc(Cl)cc3)c12
InChI Key
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 256853
Affinity DataIC50: 14nMpH: 7.5 T: 2°CAssay Description:This assay detects inhibitors of AKT1 (PKBα) kinase activity using Caliper LabChip LC3000. The Caliper off-chip incubation mobility shift assay...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Following addition of compound or control to the assay plate, 6p1 peptide mix containing 3 μM substrate (5-FAM-GRPRTSSFAEG-CONH2; CRB) and 40 ...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:For Echo dosing the solvent was 100% DMSO. A master plate was prepared with 40 ul of 10 mM stock from our Primary Liquid Store in quadrant 1 of a Lab...More data for this Ligand-Target Pair