BDBM256978 US9493432, 105

SMILES FC1(F)C[C@H](NC(=O)c2ccccc2-n2nccn2)[C@@H](C1)Nc1nc2ccc(Cl)cc2s1

InChI Key InChIKey=FYPMYKYIDBARGL-JKSUJKDBSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 256978   

TargetOrexin receptor type 2(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM256978(US9493432, 105)
Affinity DataIC50:  3.54E+3nMT: 2°CAssay Description:Orexin antagonist activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM256978(US9493432, 105)
Affinity DataIC50:  17nMT: 2°CAssay Description:Orexin antagonist activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent