BDBM25748 3-(2-{[3-(2-cyanophenoxy)-2-hydroxypropyl]amino}ethyl)-1-phenylurea::ICI 89,406::ICI 89406

SMILES OC(CNCCNC(=O)Nc1ccccc1)COc1ccccc1C#N

InChI Key InChIKey=HTLWRKRZKFAAAH-UHFFFAOYSA-N

Data  1 KI  8 Kd  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 25748   

TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
University of Nottingham

LigandPNGBDBM25748(3-(2-{[3-(2-cyanophenoxy)-2-hydroxypropyl]amino}et...)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at human beta3 adrenoceptor expressed in CHOK1 cells assessed as induction of [3H]cAMP accumulation after 5 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Ohio State University

Curated by PDSP Ki Database
LigandPNGBDBM25748(3-(2-{[3-(2-cyanophenoxy)-2-hydroxypropyl]amino}et...)
Affinity DataEC50:  60nMAssay Description:Agonist activity at human beta2 adrenoceptor expressed in CHOK1 cells assessed as induction of [3H]cAMP accumulation after 5 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM25748(3-(2-{[3-(2-cyanophenoxy)-2-hydroxypropyl]amino}et...)
Affinity DataEC50:  0.813nMAssay Description:Partial agonist activity at human beta1 adrenoceptor expressed in CHOK1 cells assessed as induction of [3H]cAMP accumulation after 5 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed