BDBM2581 3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tricosa-1(16),2(10),4(9),5,7,11(15),17(22),18,20-nonaen-12-one::CHEMBL16958::K-252c

SMILES O=C1NCc2c1c1c3ccccc3[nH]c1c1[nH]c3ccccc3c21

InChI Key InChIKey=MEXUTNIFSHFQRG-UHFFFAOYSA-N

Data  25 IC50

PDB links: 2 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2581   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Eli Lilly

LigandBDBM2581(3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^...)Copy SMILESCopy InChI

Affinity DataIC50:  830nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
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Ligand InfoPurchaseCHEMBLDrugBankPC cidPC sidPDBPatentsSimilars

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