BDBM259225 US9499502, 34
SMILES C[C@]1(CS(=O)(=O)[C@](C)(C(=N)N1)c1cccc(O)c1)c1ccc(F)cc1F
InChI Key InChIKey=RVJKKCVSYCAWNF-ROUUACIJSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 259225
Affinity DataKi: 475nM ΔG°: -8.76kcal/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
Affinity DataKi: 708nM ΔG°: -8.52kcal/molepH: 5.0 T: 2°CAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair