BDBM259837 US9505766, 41
SMILES CNC(=O)C(=C\c1ccc2[nH]nc(-c3cc(OC)c(OC)c(OC)c3)c2c1)\C#N
InChI Key InChIKey=JGIBKTCCYJBOMS-VGOFMYFVSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 259837
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents Of The University Of California
US Patent
The Regents Of The University Of California
US Patent
Affinity DataIC50: 14nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
The Regents Of The University Of California
US Patent
The Regents Of The University Of California
US Patent
Affinity DataIC50: 650nMpH: 7.6 T: 2°CAssay Description:Human PLK1 (Millipore, catalog number 14-777M) (7.2 nM) in 20 mM Hepes, pH 7.6, 10 mM MgCl2, 1 mM EDTA, 0.2 mg/mL BSA, and 100 μM ATP was pre-in...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2 [T175A](Homo sapiens (Human))
The Regents Of The University Of California
US Patent
The Regents Of The University Of California
US Patent
Affinity DataIC50: 1.14E+3nMpH: 7.6 T: 2°CAssay Description:For RSK2 kinase assays, see Example 64 above. Full-length human T175A NEK2 (referred to as NEK2) was expressed and purified as previously described (...More data for this Ligand-Target Pair