BDBM260383 US9527838, 11

SMILES COc1ccc(Sc2ccc(Sc3ccccn3)nc2C(=O)Nc2ncc(SCC(O)=O)s2)cc1

InChI Key InChIKey=BSSIABHJAVFXLM-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 260383   

TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM260383(US9527838, 11)
Affinity DataEC50:  14nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 10 mM glucose by G6PDH couple...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM260383(US9527838, 11)
Affinity DataEC50:  10.9nMAssay Description:Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E. coli, and purified on ANTIFLAG M2 AFFINITY GEL (Sigma). The assay wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent