BDBM261499 1-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)benzyl)-1,2,3,4-tetrahydroquinoline-6-carboxamide::US9708268, 2

SMILES O=COCc1ccc2NCCCc2c1

InChI Key InChIKey=COVPYEWWMSYGFI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 261499   

TargetInterleukin-17A(Homo sapiens (Human))
Innov17

US Patent
LigandPNGBDBM261499(1-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)...)
Affinity DataIC50: <1.00E+4nMAssay Description:Human CD4+ T cells were differentiated to TH17 cells as described in the presence or absence of various concentrations of compounds in a final concen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Innov17

US Patent
LigandPNGBDBM261499(1-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)...)
Affinity DataIC50: <1.00E+4nMAssay Description:Compound binding to the human RORγ LBD was assessed using the Human RORγ Assay System (INDIGO Biosciences Inc.) as per manufacturer's i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-22 receptor subunit alpha-2(Homo sapiens (Human))
Innov17

US Patent
LigandPNGBDBM261499(1-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)...)
Affinity DataIC50: <1.00E+4nMAssay Description:Human CD4+ T cells were differentiated to TH17 cells as described in the presence or absence of various concentrations of compounds in a final concen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-17F(Homo sapiens (Human))
Innov17

US Patent
LigandPNGBDBM261499(1-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)...)
Affinity DataIC50: <1.00E+4nMAssay Description:Human CD4+ T cells were differentiated to TH17 cells as described in the presence or absence of various concentrations of compounds in a final concen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent