BDBM261508 1-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)benzyl)indoline-5-carboxamide::US9708268, 11

SMILES Brc1ccc2NCCc2c1

InChI Key InChIKey=QEDCHCLHHGGYBT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 261508   

TargetInterleukin-17A(Homo sapiens (Human))
Innov17

US Patent
LigandPNGBDBM261508(1-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)...)
Affinity DataIC50: <1.00E+4nMAssay Description:Human CD4+ T cells were differentiated to TH17 cells as described in the presence or absence of various concentrations of compounds in a final concen...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInterleukin-22 receptor subunit alpha-2(Homo sapiens (Human))
Innov17

US Patent
LigandPNGBDBM261508(1-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Human CD4+ T cells were differentiated to TH17 cells as described in the presence or absence of various concentrations of compounds in a final concen...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInterleukin-17F(Homo sapiens (Human))
Innov17

US Patent
LigandPNGBDBM261508(1-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)...)
Affinity DataIC50: <1.00E+4nMAssay Description:Human CD4+ T cells were differentiated to TH17 cells as described in the presence or absence of various concentrations of compounds in a final concen...More data for this Ligand-Target Pair
In DepthDetails US Patent