BDBM263455 (s)-2-(6-chloro-4-oxobenzo[d][1,2,3]triazin-3(4h)-yl)-n-(1-(4-methoxyphenyl)ethyl)acetamide::US10561662, Example 20::US11173161, EX 20::US9556130, test 20
SMILES COc1ccc(cc1)[C@H](C)NC(=O)Cn1nnc2ccc(Cl)cc2c1=O
InChI Key InChIKey=IMHMUHMELFJCBS-NSHDSACASA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 263455
Affinity DataKi: 551nM ΔG°: -7.93kcal/molepH: 7.4 T: 2°CAssay Description:This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec...More data for this Ligand-Target Pair
Affinity DataKi: 551nMAssay Description:Membranes were removed from −80° C., thawed and diluted in cold radioligand assay buffer (20 mM HEPES pH 7.4/5 mM MgCl2/1 mM CaCl2/Roche protea...More data for this Ligand-Target Pair
Affinity DataKi: 5.51E+5nMAssay Description:This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec...More data for this Ligand-Target Pair