BDBM263553 2-{5-amino-1-[2-chloro-4-(3- cyano-phenoxy)-phenyl]-1h- pyrazole-4-carbonyl}-n-cyano- 1h-indole-5-carboxylic acid amide::US9556150, i-41

SMILES Nc1c(cnn1-c1ccc(Oc2cccc(c2)C#N)cc1Cl)C(=O)c1cc2cc(ccc2[nH]1)C(=O)NC#N

InChI Key InChIKey=DWFZKHPBAFWVNS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 263553   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM263553(2-{5-amino-1-[2-chloro-4-(3- cyano-phenoxy)-phenyl...)
Affinity DataIC50:  52nMpH: 7.15Assay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Förster/Fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent