BDBM264265 6-(2,6-Dichlorophenyl)-2-((4-morpholinophenyl)amino)pyrido[4,3-d]pyrimidin-5(6H)-one::US9714244, 19

SMILES Clc1cccc(Cl)c1-n1ccc2nc(Nc3ccc(cc3)N3CCOCC3)ncc2c1=O

InChI Key InChIKey=KJFOURHTDLDEJK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 264265   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Almac Discovery

US Patent
LigandPNGBDBM264265(6-(2,6-Dichlorophenyl)-2-((4-morpholinophenyl)amin...)
Affinity DataIC50: <10nMAssay Description:Compounds were tested for inhibition of the human ether a go-go related gene (hERG) K+ channel using IonWorks patch clamp electrophysiology at Essen ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetWee1-like protein kinase(Homo sapiens (Human))
Almac Discovery

US Patent
LigandPNGBDBM264265(6-(2,6-Dichlorophenyl)-2-((4-morpholinophenyl)amin...)
Affinity DataIC50:  5.50E+3nMT: 2°CAssay Description:In the measurement of Wee-1 activity, a commercial peptide Poly(Lys Tyr(4:1)) hydrobromide was purchased from Sigma Aldrich and used as the substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent