BDBM264456 6-(4-chlorophenyl)-5-(1,5-dimethyl-6-oxo-1,6-dihydropyridin-3-yl)-1-(2-methoxypyrimidin-5-yl)-3-methyl-5,6-dihydropyrrolo[3,4-c]pyrazol-4(1H)-one and::US9714249, 21a
SMILES COc1ncc(NC2=C(C(C)=N)C(=O)N(C2c2ccc(Cl)cc2)c2cc(C)c(=O)n(C)c2)cn1
InChI Key InChIKey=BHZGECKOYMLRSO-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 264456
Affinity DataIC50: 71nMpH: 7.5Assay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
Affinity DataIC50: >1.11E+4nMpH: 7.5 T: 2°CAssay Description:In order to assess bromodomain selectivity, we set up a binding assay using the bromodomain encoded by the CREBBP gene. Compounds were tested in the ...More data for this Ligand-Target Pair
Affinity DataIC50: 52nMpH: 7.5Assay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
Affinity DataIC50: 63nMpH: 7.5Assay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair