BDBM26549 (3R)-1-{[4-(but-2-yn-1-ylamino)benzene]sulfonyl}pyrrolidine-3-thiol::thiol-arylsulfonamide, 16b

SMILES CC#CCNc1ccc(cc1)S(=O)(=O)N1CC[C@@H](S)C1

InChI Key InChIKey=PWEZTWADIIJUFX-CYBMUJFWSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26549   

LigandPNGBDBM26549((3R)-1-{[4-(but-2-yn-1-ylamino)benzene]sulfonyl}py...)
Affinity DataKi:  5nM ΔG°:  -11.2kcal/molepH: 7.5 T: 2°CAssay Description:The compounds were tested for TACE inhibition using fluorescence resonance energy transfer (FRET) assay. TACE catalyzed cleavage of the substrate pep...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed