BDBM26549 (3R)-1-{[4-(but-2-yn-1-ylamino)benzene]sulfonyl}pyrrolidine-3-thiol::thiol-arylsulfonamide, 16b
SMILES CC#CCNc1ccc(cc1)S(=O)(=O)N1CC[C@@H](S)C1
InChI Key InChIKey=PWEZTWADIIJUFX-CYBMUJFWSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 26549
TargetDisintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q](Homo sapiens (Human))
Vertex Pharmaceuticals
Vertex Pharmaceuticals
Affinity DataKi: 5nM ΔG°: -11.2kcal/molepH: 7.5 T: 2°CAssay Description:The compounds were tested for TACE inhibition using fluorescence resonance energy transfer (FRET) assay. TACE catalyzed cleavage of the substrate pep...More data for this Ligand-Target Pair