BDBM26574 (3R,4R)-4-N-[4-({2-tert-butylpyrazolo[1,5-a]pyridin-3-yl}methyl)benzene]-3-N-hydroxyoxane-3,4-dicarboxamide::pyrazolopyridine, 48

SMILES CC(C)(C)c1nn2ccccc2c1Cc1ccc(cc1)C(=O)N[C@@H]1CCOC[C@@H]1C(=O)NO

InChI Key InChIKey=KCBXQUWPZNVZIG-VQTJNVASSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 26574   

TargetMacrophage metalloelastase(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM26574((3R,4R)-4-N-[4-({2-tert-butylpyrazolo[1,5-a]pyridi...)
Affinity DataKi:  726nMAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM26574((3R,4R)-4-N-[4-({2-tert-butylpyrazolo[1,5-a]pyridi...)
Affinity DataKi: >3.33E+3nMAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM26574((3R,4R)-4-N-[4-({2-tert-butylpyrazolo[1,5-a]pyridi...)
Affinity DataKi: >4.50E+3nMAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM26574((3R,4R)-4-N-[4-({2-tert-butylpyrazolo[1,5-a]pyridi...)
Affinity DataKi: >6.37E+3nMAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Bristol-Myers Squibb

LigandPNGBDBM26574((3R,4R)-4-N-[4-({2-tert-butylpyrazolo[1,5-a]pyridi...)
Affinity DataIC50:  2.80nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed