BDBM267470 US9718822, 45 Diastereomer 2

SMILES O[C@@H]1CNC(=O)c2cnn3ccc(nc23)N2CC(F)(F)CC2c2cc(F)ccc2OC1

InChI Key InChIKey=RQZIXOOARXBNHW-KEKZHRQWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 267470   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM267470(US9718822, 45 Diastereomer 2)
Affinity DataIC50:  55nMpH: 7.5Assay Description:The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen¿ Eu Kinase Binding Assay. In this assay, His-tagged recombina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent