BDBM268449 4-[6-(azetidine-1-carbonyl)-3-(2- chloro-6-cyclopropyl- benzoyl)imidazo[1,5-a]pyridin-1- yl]benzoic acid::US9550771, Example 48

SMILES OC(=O)c1ccc(cc1)-c1nc(C(=O)c2c(Cl)cccc2C2CC2)n2cc(ccc12)C(=O)N1CCC1

InChI Key InChIKey=KJKQXUULNHCCHZ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 268449   

TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268449(4-[6-(azetidine-1-carbonyl)-3-(2- chloro-6-cyclopr...)
Affinity DataEC50:  3nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent