BDBM268491 4-[3-(2-chloro-6-cyclopropyl- benzoyl)-5,6,7,8- tetrahydroimidazo[1,5-a]pyridin- 1-yl]-2-hydroxy-5-methyl- benzoic acid; formic acid::US9550771, Example 90

SMILES Cc1cc(C(O)=O)c(O)cc1-c1nc(C(=O)c2c(Cl)cccc2C2CC2)n2CCCCc12

InChI Key InChIKey=UVNSKDMDTJPPIC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 268491   

TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268491(4-[3-(2-chloro-6-cyclopropyl- benzoyl)-5,6,7,8- te...)
Affinity DataEC50:  9nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent