BDBM26908 8-[bis(2-chlorophenyl)methyl]-3-[2-(cyclopentylamino)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::spiropiperidine analogue, 29

SMILES Clc1ccccc1C(N1CCC2(CC1)N(CN(CCNC1CCCC1)C2=O)c1ccccc1)c1ccccc1Cl

InChI Key InChIKey=SBLIYIIALWZVLS-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 26908   

TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM26908(8-[bis(2-chlorophenyl)methyl]-3-[2-(cyclopentylami...)
Affinity DataKi:  8.65nM ΔG°:  -10.9kcal/molepH: 7.4 T: 2°CAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM26908(8-[bis(2-chlorophenyl)methyl]-3-[2-(cyclopentylami...)
Affinity DataKi:  247nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM26908(8-[bis(2-chlorophenyl)methyl]-3-[2-(cyclopentylami...)
Affinity DataKi:  625nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM26908(8-[bis(2-chlorophenyl)methyl]-3-[2-(cyclopentylami...)
Affinity DataKi:  1.53E+3nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed