BDBM26951 3-[2-(benzylamino)ethyl]-8-(4,4-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::spiropiperidine analogue, 69

SMILES CC1(C)CCC(N2CCC3(CC2)N(CN(CCNCc2ccccc2)C3=O)c2ccccc2)c2ccccc12

InChI Key InChIKey=GZSRIFUGJZDLKC-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 26951   

TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM26951(3-[2-(benzylamino)ethyl]-8-(4,4-dimethyl-1,2,3,4-t...)
Affinity DataKi:  3.60nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM26951(3-[2-(benzylamino)ethyl]-8-(4,4-dimethyl-1,2,3,4-t...)
Affinity DataKi:  139nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM26951(3-[2-(benzylamino)ethyl]-8-(4,4-dimethyl-1,2,3,4-t...)
Affinity DataKi:  151nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM26951(3-[2-(benzylamino)ethyl]-8-(4,4-dimethyl-1,2,3,4-t...)
Affinity DataKi:  1.28E+3nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed