BDBM26979 BDBM50494542::CHEMBL69710::Cl-::POTASSIUM CHLORIDE::SODIUM CHLORIDE::chloride::chloride ion
SMILES [Cl-]
InChI Key InChIKey=VEXZGXHMUGYJMC-UHFFFAOYSA-M
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 54 hits for monomerid = 26979
Affinity DataIC50: 6.53E+3nMAssay Description:Inhibition of human recombinant GSK3beta using prephosphorylated GS1 peptide as substrate after 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataEC50: >3.00E+6nMAssay Description:Effective concentration of compound against glycogen synthase kinase-3 in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 8.53E+4nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 9.00E+4nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 9.00E+4nMAssay Description:Inhibition of human carbonic anhydrase 4 by Lineweaver-Burk curvesMore data for this Ligand-Target Pair
Affinity DataKi: 9.00E+4nMAssay Description:Inhibition constant of anion against human carbonic anhydrase isozyme hCA IVMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+8nMAssay Description:Inhibition of human cytosolic carbonic anhydrase-2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase(Methanobacterium thermoautotrophicum)
Universita Degli Studi Di Firenze
Curated by ChEMBL
Universita Degli Studi Di Firenze
Curated by ChEMBL
Affinity DataKi: 1.52E+8nMAssay Description:Inhibitory constant against methanoarchaeon Methanobacterium thermoautotrophicum (Cab)More data for this Ligand-Target Pair
Affinity DataKi: 1.84E+6nMAssay Description:Inhibition of human recombinant CA7More data for this Ligand-Target Pair
Affinity DataKi: 3.30E+7nMAssay Description:Inhibition constant of anion against human carbonic anhydrase isozyme hCA IXMore data for this Ligand-Target Pair
Affinity DataKi: 6.00E+6nMAssay Description:Inhibition constant of anion against human carbonic anhydrase isozyme hCA IMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+8nMAssay Description:Inhibition constant of anion against human carbonic anhydrase isozyme hCA IIMore data for this Ligand-Target Pair
Affinity DataKi: 1.38E+8nMAssay Description:Inhibitory activity against mouse carbonic anhydrase XIII expressed in Escherichia coli TOP 10More data for this Ligand-Target Pair
Affinity DataKi: 6.00E+6nMAssay Description:Inhibitory activity against human carbonic anhydrase I expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+8nMAssay Description:Inhibitory activity against human carbonic anhydrase II expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 3.60E+7nMAssay Description:Inhibitory constant against carbonic anhydrase IVMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+8nMAssay Description:Inhibitory constant against carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 6.00E+6nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+8nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+8nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+8nMAssay Description:Inhibition of human recombinant wild type CA2 by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 6.00E+6nMAssay Description:Inhibition of human recombinant wild type CA1 by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+8nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.00E+6nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase(Methanosarcina thermophila)
Universita Degli Studi Di Firenze
Curated by ChEMBL
Universita Degli Studi Di Firenze
Curated by ChEMBL
Affinity DataKi: >2.00E+8nMAssay Description:Inhibitory constant against Zn-Cam (Methanosarcina thermophila)More data for this Ligand-Target Pair
Affinity DataKi: 6.00E+6nMAssay Description:Inhibition of human carbonic anhydrase 1 by Lineweaver-Burk curvesMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+8nMAssay Description:Inhibition of human carbonic anhydrase 2 by Lineweaver-Burk curvesMore data for this Ligand-Target Pair
Affinity DataKi: 1.56E+8nMAssay Description:Inhibition of human carbonic anhydrase 5 by Lineweaver-Burk curvesMore data for this Ligand-Target Pair
Affinity DataKi: 3.30E+7nMAssay Description:Inhibition of human carbonic anhydrase 9 by Lineweaver-Burk curvesMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+8nMAssay Description:Inhibition of human carbonic anhydrase-2 by [18O]-exchange mass spectroscopyMore data for this Ligand-Target Pair
Affinity DataKi: 6.00E+6nM ΔG°: -2.98kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+8nM ΔG°: -0.937kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 2.70E+6nM ΔG°: -3.50kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity Khalifah RG. The carbon dioxide hy...More data for this Ligand-Target Pair
Affinity DataKi: 5.60E+5nM ΔG°: -4.43kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity Khalifah RG. The carbon dioxide hy...More data for this Ligand-Target Pair
Affinity DataKi: 6.00E+6nM ΔG°: -2.98kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+8nM ΔG°: -0.937kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition of Helicobacter pylori alpha carbonic anhydrase preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.70E+6nM ΔG°: -3.44kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition of Vibrio cholerae alpha carbonic anhydrase preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase(Vibrio cholerae serotype O1 (strain ATCC 39315 / E...)
Universita Degli Studi Di Firenze
Universita Degli Studi Di Firenze
Affinity DataKi: 9.30E+6nM ΔG°: -2.72kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition of Flaveria bidentis carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair