BDBM270543 US10059688, Example 115::US9783524, Example 115
SMILES CN(C)CCOc1ccc(Nc2ncc(Cl)c(Nc3ccccc3C(=O)C(=O)N(C)C)n2)cc1NC(=O)C=C
InChI Key InChIKey=WSDSYYCVRCLNSN-UHFFFAOYSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 270543
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Betta Pharmaceuticals
US Patent
Betta Pharmaceuticals
US Patent
Affinity DataIC50: 397nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
Affinity DataIC50: 8.62nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514) 1. 2.5 uL-4x Test Compound or 100 nL 100x plus 2.4...More data for this Ligand-Target Pair
Affinity DataIC50: 547nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Betta Pharmaceuticals
US Patent
Betta Pharmaceuticals
US Patent
Affinity DataIC50: 11.7nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
Affinity DataIC50: 18.7nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair