BDBM272089 (S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-2-(m- tolyl)-2,4,5,6-tetrahydrocyclopenta[c]pyrazole-5- carboxamide::US10065948, 25::US10457675, Example 25

SMILES Cc1cccc(c1)-n1cc2C[C@@](Cc2n1)(C(=O)NO)c1cccc(F)c1C

InChI Key InChIKey=LOAYEJGESQGNOL-NRFANRHFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 272089   

TargetHistone deacetylase 9(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM272089((S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-2-(m- to...)
Affinity DataIC50:  76nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 9(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM272089((S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-2-(m- to...)
Affinity DataIC50:  76nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent