BDBM272113 (R)-2-(2-Chlorophenyl)-5-(3-fluoro-2-methylphenyl)- N-hydroxy-6,7-dihydro-5H-cyclopenta[d]pyrimidine- 5-carboxamide::US10065948, 49::US10457675, Example 49

SMILES Cc1c(F)cccc1[C@@]1(CCc2nc(ncc12)-c1ccccc1Cl)C(=O)NO

InChI Key InChIKey=CBWMOTKRRHVTON-OAQYLSRUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 272113   

TargetHistone deacetylase 9(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM272113((R)-2-(2-Chlorophenyl)-5-(3-fluoro-2-methylphenyl)...)
Affinity DataIC50:  102nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 9(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM272113((R)-2-(2-Chlorophenyl)-5-(3-fluoro-2-methylphenyl)...)
Affinity DataIC50:  102nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent