BDBM272116 (S)-2-Cyclopropyl-6-(3-fluoro-2-methylphenyl)-N- hydroxy-6,7-dihydro-5H-cyclopenta[d]pyrimidine-6- carboxamide::US10065948, 52::US10457675, Example 52

SMILES Cc1c(F)cccc1[C@@]1(Cc2cnc(nc2C1)C1CC1)C(=O)NO

InChI Key InChIKey=RBXLMMUKOIVVKT-SFHVURJKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 272116   

TargetHistone deacetylase 9(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM272116((S)-2-Cyclopropyl-6-(3-fluoro-2-methylphenyl)-N- h...)
Affinity DataIC50:  160nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 9(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM272116((S)-2-Cyclopropyl-6-(3-fluoro-2-methylphenyl)-N- h...)
Affinity DataIC50:  160nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent