BDBM27212 (2S)-2-acetamido-N-methyl-3-phenyl-N-[(1R,2S,5S,6S,9R,12S,13R,16S)-6,7,13-trimethyl-7-azapentacyclo[10.8.0.0^{2,9}.0^{5,9}.0^{13,18}]icos-18-en-16-yl]propanamide::Conessine analogue, 13e

SMILES [H][C@@]1(C)N(C)C[C@]23CC[C@@]4([H])[C@@]([H])(CC=C5C[C@H](CC[C@]45C)N(C)C(=O)[C@H](Cc4ccccc4)NC(C)=O)[C@]2([H])CC[C@]13[H]

InChI Key InChIKey=XUMAXPIIUJYLNX-OLFWIATPSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 27212   

TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27212((2S)-2-acetamido-N-methyl-3-phenyl-N-[(1R,2S,5S,6S...)
Affinity DataKi:  1.15nM ΔG°:  -12.2kcal/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbott Laboratories

LigandPNGBDBM27212((2S)-2-acetamido-N-methyl-3-phenyl-N-[(1R,2S,5S,6S...)
Affinity DataKi:  2.29nMAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed