BDBM273013 (R)-N-(2-chlorobenzyl)-2-[7-oxo-6-(propan-2-yl)-5-trifluoromethyl-6,7-dihydro[1,3]thiazolo[5,4-d]pyrimidin-2-yl]pyrrolidine-1-carboxamide::US10065972, Example 11

SMILES CC(C)n1c(nc2sc(nc2c1=O)[C@H]1CCCN1C(=O)NCc1ccccc1Cl)C(F)(F)F

InChI Key InChIKey=PMWSFCNKWRKFDM-CQSZACIVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 273013   

TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM273013((R)-N-(2-chlorobenzyl)-2-[7-oxo-6-(propan-2-yl)-5-...)
Affinity DataIC50:  6.20E+3nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent