BDBM273018 (R)-2-(5-ethyl-6-methyl-7-oxo-6,7-dihydro[1,3]thiazolo[5,4-d]pyrimidin-2-yl)-N-((R)-1-phenylethyl)pyrrolidine-1-carboxamide::US10065972, Example 17

SMILES CCc1nc2sc(nc2c(=O)n1C)[C@H]1CCCN1C(=O)N[C@H](C)c1ccccc1

InChI Key InChIKey=APHQRQWOTRYIOK-UKRRQHHQSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 273018   

TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM273018((R)-2-(5-ethyl-6-methyl-7-oxo-6,7-dihydro[1,3]thia...)
Affinity DataIC50:  1.60E+3nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent