BDBM273042 2-[5-(2-fluoropropan-2-yl)-7-oxo-6,7-dihydro[1,3]thiazolo[5,4-d]pyrimidin-2-yl]pyrazolidine-1-carboxylic acid phenyl ester::US10065972, Example 131

SMILES CC(C)(F)c1nc2sc(nc2c(=O)[nH]1)N1CCCN1C(=O)Oc1ccccc1

InChI Key InChIKey=IYQSZIRIQMYGTJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 273042   

TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM273042(2-[5-(2-fluoropropan-2-yl)-7-oxo-6,7-dihydro[1,3]t...)
Affinity DataIC50:  110nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent