BDBM273045 5-(2-fluoropropan-2-yl)-2-{2-[2-(3-methylphenyl) acetyl]pyrazolidin-1-yl}-6H-[1,3]thiazolo[5,4-d]pyrimidin-7-one::US10065972, Example 134
SMILES Cc1cccc(CC(=O)N2CCCN2c2nc3c(nc([nH]c3=O)C(C)(C)F)s2)c1
InChI Key InChIKey=WDOAXUIRSFMVDJ-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 273045
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
US Patent
Mitsubishi Tanabe Pharma
US Patent
Affinity DataIC50: 230nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair