BDBM273045 5-(2-fluoropropan-2-yl)-2-{2-[2-(3-methylphenyl) acetyl]pyrazolidin-1-yl}-6H-[1,3]thiazolo[5,4-d]pyrimidin-7-one::US10065972, Example 134

SMILES Cc1cccc(CC(=O)N2CCCN2c2nc3c(nc([nH]c3=O)C(C)(C)F)s2)c1

InChI Key InChIKey=WDOAXUIRSFMVDJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 273045   

TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM273045(5-(2-fluoropropan-2-yl)-2-{2-[2-(3-methylphenyl) a...)
Affinity DataIC50:  230nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent