BDBM273047 (R)-2-[6-(2-fluorophenyl)-4-oxo-4,5-dihydro[1,3]thiazolo[4,5-c]pyridin-2-yl]pyrrolidine-1-carboxylic acid phenyl ester::US10065972, Example 137
SMILES Fc1ccccc1-c1cc2sc(nc2c(=O)[nH]1)[C@H]1CCCN1C(=O)Oc1ccccc1
InChI Key InChIKey=BCSFKCDCDLTLQE-GOSISDBHSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 273047
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
US Patent
Mitsubishi Tanabe Pharma
US Patent
Affinity DataIC50: 69nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair