BDBM273049 (R)-2-[5-oxo-7-(propan-2-yl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-2-yl]pyrrolidine-1-carboxylic acid 4-fluorophenyl ester::US10065972, Example 140
SMILES CC(C)c1cc(=O)n2nc(sc2n1)[C@H]1CCCN1C(=O)Oc1ccc(F)cc1
InChI Key InChIKey=IAWBLQZNXDMCGW-OAHLLOKOSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 273049
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
US Patent
Mitsubishi Tanabe Pharma
US Patent
Affinity DataIC50: 77nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair