BDBM273057 (R)-2-[6-chloro-5-oxo-7-(propan-2-yl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-2-yl]pyrrolidine-1-carboxylic acid phenyl ester::US10065972, Example 153
SMILES CC(C)c1nc2sc(nn2c(=O)c1Cl)[C@H]1CCCN1C(=O)Oc1ccccc1
InChI Key InChIKey=WKQFKXAXDIGBPQ-CYBMUJFWSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 273057
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
US Patent
Mitsubishi Tanabe Pharma
US Patent
Affinity DataIC50: 48nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair