BDBM273146 (R)-N-benzyl-1-(5-cyclopropyl-6-methyl-7-oxo-6,7-dihydro[1,3]thiazolo[5,4-d]pyrimidin-2-yl)-4,4-difluoropyrrolidine-2-carboxamide::US10065972, Example 572
SMILES Cn1c(nc2sc(nc2c1=O)N1CC(F)(F)C[C@@H]1C(=O)NCc1ccccc1)C1CC1
InChI Key InChIKey=GBLQKTAOQFIEQU-CQSZACIVSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 273146
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
US Patent
Mitsubishi Tanabe Pharma
US Patent
Affinity DataIC50: 86nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair