BDBM273150 5-ethyl-6-methyl-2-[(R)-2-(2-phenylaminoacetyl)pyrrolidin-1-yl][1,3]thiazolo[5,4-d]pyrimidin-7(6H)-one::US10065972, Example 579

SMILES CCc1nc2sc(nc2c(=O)n1C)N1CCC[C@@H]1C(=O)CNc1ccccc1

InChI Key InChIKey=ANYNYCMITFVKDA-CQSZACIVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 273150   

TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM273150(5-ethyl-6-methyl-2-[(R)-2-(2-phenylaminoacetyl)pyr...)
Affinity DataIC50:  10nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent