BDBM273154 (R)-N-benzyl-1-[6-(2,2-difluoroethyl)-10-oxo-5,7,8,10-tetrahydro-6H-pyrazino[1,2-a][1,3]thiazolo[5,4-d]pyrimidin-2-yl]pyrrolidine-2-carboxamide::US10065972, Example 593
SMILES FC(F)CN1CCn2c(C1)nc1sc(nc1c2=O)N1CCC[C@@H]1C(=O)NCc1ccccc1
InChI Key InChIKey=BJCQIUTWSAVAPS-OAHLLOKOSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 273154
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
US Patent
Mitsubishi Tanabe Pharma
US Patent
Affinity DataIC50: 51nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair