BDBM273160 (2R,3R)-3-amino-N-benzyl-1-(6-methyl-7-oxo-5-phenyl-6,7-dihydro[1,3]thiazolo[5,4-d]pyrimidin-2-yl)pyrrolidine-2-carboxamide::US10065972, Example 611

SMILES Cn1c(nc2sc(nc2c1=O)N1CC[C@@H](N)[C@@H]1C(=O)NCc1ccccc1)-c1ccccc1

InChI Key InChIKey=LCKYADILADCSKT-IEBWSBKVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 273160   

TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM273160((2R,3R)-3-amino-N-benzyl-1-(6-methyl-7-oxo-5-pheny...)
Affinity DataIC50:  570nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent