BDBM273170 (R)-N-benzyl-1-(5-methyl-4-oxo-6-trifluoromethyl-4,5-dihydro[1,3]thiazolo[4,5-c]pyridin-2-yl)pyrrolidine-2-carboxamide::US10065972, Example 631

SMILES Cn1c(cc2sc(nc2c1=O)N1CCC[C@@H]1C(=O)NCc1ccccc1)C(F)(F)F

InChI Key InChIKey=SVNFKAUMHXBKER-CYBMUJFWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 273170   

TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM273170((R)-N-benzyl-1-(5-methyl-4-oxo-6-trifluoromethyl-4...)
Affinity DataIC50:  55nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent