BDBM273170 (R)-N-benzyl-1-(5-methyl-4-oxo-6-trifluoromethyl-4,5-dihydro[1,3]thiazolo[4,5-c]pyridin-2-yl)pyrrolidine-2-carboxamide::US10065972, Example 631
SMILES Cn1c(cc2sc(nc2c1=O)N1CCC[C@@H]1C(=O)NCc1ccccc1)C(F)(F)F
InChI Key InChIKey=SVNFKAUMHXBKER-CYBMUJFWSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 273170
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
US Patent
Mitsubishi Tanabe Pharma
US Patent
Affinity DataIC50: 55nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair