BDBM273171 (R)-N-benzyl-1-(5-oxo-7-propyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-2-yl) piperidine-2-carboxamide::US10065972, Example 635

SMILES CCCc1cc(=O)n2nc(sc2n1)N1CCCC[C@@H]1C(=O)NCc1ccccc1

InChI Key InChIKey=HFRFGEWASUXNDS-QGZVFWFLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 273171   

TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM273171((R)-N-benzyl-1-(5-oxo-7-propyl-5H-[1,3,4]thiadiazo...)
Affinity DataIC50:  970nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent